Case Studies
Zinc and the Common Cold
A class-action against the manufacturer of Cold-Eeze® lozenges alleged that the product had not been ¡°clinically proven¡± to ameliorate cold symptoms as claimed. The available clinical studies varied in methodology and were difficult to interpret unambiguously. However, Dr. Weisberg¡¯s thorough review of the research indicated that the weight of evidence, including two randomized clinical trials of the product, generally supported the hypothesis that the product was effective. His testimony at trial was highly influential in convincing a jury that sufficient evidence existed to uphold the company¡¯s claims.
PPA and Strokes
In a single large retrospective study, an apparent increase in the risk of hemorrhagic stroke was attributed to use of phenylpropanolamine (PPA), a widely used ingredient in cold and cough remedies and some diet pills. Subsequently, hundreds of lawsuits were lodged against the manufacturers of PPA-containing products. On behalf of a leading pharmaceutical company, CRI undertook a re-analysis of the data upon which the study was based and produced an extensive report. This report revealed a number of critical weaknesses in the evidence supporting a possible causal link between PPA and strokes.
Listeria Outbreak
This product liability case was brought by a group of plaintiffs who had contracted a disease known as listeriosis, which can be serious when affecting the elderly or others with weakened immune systems. A CDC study suggested that milk from a certain large New England supermarket chain was the source of the listeria (bacteria) that caused this outbreak. Extensive biostatistical research by CRI provided powerful epidemiological evidence that supported the defendant#39;s contention of an alternative source.
Disgruntled Engineer
This employment discrimination case involved an engineer at a large government supported research laboratory. This individual alleged discrimination based on the system of personnel evaluations at the facility. CRI undertook a detailed analysis of the system, and determined that the system was essentially fair. The defendant prevailed at a trial in federal district court.
Race and Police Promotions
In this employment discrimination case, an urban police department was accused of favoring non-minority officers for promotion. CRI performed a study that involved sampling the employment records to test the allegations. The records showed that ethnic differences had a non-discrimination explanation. A favorable settlement was eventually reached, based in large part on the results obtained.
Dueling Drugs
This case involved a dispute over advertising claims by a major pharmaceutical manufacturer. The manufacturer of a new blood pressure medication claimed that its product was superior to our client#39;s on the basis of clinical trials conducted to support a marketing campaign. CRI performed a number of re-analyses of the clinical trials data and provided strong evidence to counter these claims, helping to achieve a successful negotiated settlement.
Insurance Fraud Proof
CRI was retained to assist in the criminal and then later the civil prosecution for insurance fraud of a Boston area medical provider. CRI extracted data from hundreds of medical records to demonstrate a pattern of practice consistent with insurance fraud. Dr. Weisberg#39;s testimony proved crucial in convincing the jury to award a multi-million dollar judgment to the insurance company defrauded.
Dangerous Toy Chests
In this unusual product liability case, a large retailer was sued for failing to warn customers about risks associated with a certain toy chest. A number of children had been injured by a heavy wooden lid. CRI supervised a customer survey to learn whether the instructions for use of the product were adequate.
